One fifth of research papers on the subject of genetics are marred by errors attributable to Microsoft Excel.
A report published in BioMed Central suggested that the errors were caused by Excel's zealotry in converting numbers into dates.
The researchers, Mark Ziemann, Yotam Eren and Assam El-Osta, suggested that the errors are easily made when using Microsoft Excel's default settings.
"The spreadsheet software Microsoft Excel, when used with default settings, is known to convert gene names to dates and floating-point numbers," said the report.
"A programmatic scan of leading genomics journals reveals that approximately one fifth of papers with supplementary Excel gene lists contain erroneous gene name conversions."
The problem has been rife since 2004, just three years before it emerged that Excel couldn't cope with anything involving the number 65,535.
Many of the problems involve simple misreading of information such as dates. The report said that gene symbols SEPT2 (Septin 2) and MARCH1 (Membrane-Associated Ring Finger) are converted by Excel into 2-Sep and 1-Mar, thus completely removing their point.
RIKEN identifiers are automatically converted by Excel into floating point numbers, the researchers found, for example from accession 2310009E13 to 2.31E+13. SEPT2 has been converted into 2006/09/02.
This is all starting to get a bit complicated, but the problem is obvious: you don't mess with genetics. Stupid errors with DNA led to Jurassic Park's untimely disaster (three of them, in fact).
And while "Life finds a way" may be a stretch when applied to nature bending its wrath around stubbornly coded spreadsheets, we could be looking at an army of giant Clippys launching an attack on the mainland if we're not too careful.
"Supplementary files in Excel format from 18 journals published from 2005 to 2015 were programmatically screened for the presence of gene name errors. We screened 35,175 supplementary Excel files, finding 7,467 gene lists attached to 3,597 published papers," concluded the report.
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