Microsoft and Adobe have released security patches to address vulnerabilities across a range of products.
The Microsoft Patch Tuesday update addresses 34 vulnerabilities in Windows, Silverlight, Office and Internet Explorer. The flaws are covered by 16 bulletins, nine of which have been classified as 'critical'.
If exploited, the flaws in the critical bulletins could allow an attacker to remotely execute code on a targeted system without user interaction or notification.
The nine remaining bulletins are listed as 'important' and include a fix for a remote code execution flaw in Office. The company said that an attacker could use a specially crafted Excel file to exploit the flaw on a targeted system.
The Adobe update, meanwhile, addresses critical security flaws in the Windows and OS X versions of Adobe Reader and Acrobat.
Dave Marcus, head of research and communications at McAfee Labs, advised administrators to evaluate the patches and prioritise the highest-risk vulnerabilities for deployment.
"There's going to be a lot of heavy lifting for IT administrators this month with a large number of Microsoft, Adobe and Java patches," he said.
Sophos senior technology consultant Graham Cluley noted in a blog post that the nature of the patches make deployment more difficult than normal for IT staff.
"What may create even more of a headache for some system administrators is that many of the patches will require Windows computers to be rebooted," he wrote.
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