London currently tops all cities in number of Twitter users, according to the company.
In an interview with the BBC, founder Evan Williams said that London has more users than any city, topping traditional tech hotspots such as New York, San Francisco and San Jose.
"We have definitely noticed that the UK has exploded for us recently," said Williams.
"The UK is second only to the US in number of Twitter users."
Williams also commented on the microblogging service's impact on journalism and shrugged off the notion that Twitter is creating a false sense of community within its user base.
"It's not any less real than using a telephone to communicate," he said.
"There is a lot of friend communication that goes on with Twitter mixed with news, celebrities, business, you name it."
The Twitter co-founder's comments come just as many organisations are dealing with the new opportunities and challenges afforded by the service.
While Twitter has allowed users to quickly communicate information about live events and news developments, information leaks and foolish posts have plagued many of the service's high-profile users.
Worries about data leaks recently forced the United States Marines to ban soldiers from using the service.
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