The company will walk away from nine years of its £1.97bn 10-year contract, and will pay back £63m of the £173m it has already been paid by the NHS. An undisclosed number of Accenture staff will transfer to CSC.
Accenture is transferring responsibility for GP and hospital IT in the North East and East clusters to CSC, but will retain responsibility for delivering the Picture Archiving and Communications System.
CSC has responsibility for the North, North West, Midlands and West clusters.
Accenture has not made public the reason for its departure from NPfIT, but press reports have pointed to the difficulty the firm has had in envisaging a profitable outcome from the contract.
Delays in delivering Lorenzo have caused considerable angst at Accenture, and contributed to the financial woes of iSoft which announced a £348.3m loss in August.
Microsoft receives a 30 per cent cut of all purchases on the Xbox digital store
Credit card thieves used Apple ID accounts to buy and sell virtual currency for Clash of Clans and Clash Royale and Marvel Contest of Champions
$5.1bn fine further evidence that the EU is anti-US, claims Trump
New cable will connect Virginia to France