The game, which was briefly withdrawn from sale in the US after softcore pornography was found on it, won five of the 19 awards at the ceremony.
The two lead characters won Best Villain and Best Hero, while the game as a whole won Best Soundtrack, PS2 Game of the Year and Ultimate Game of 2005.
The Golden Joystick Awards was set up in 1982 to celebrate the best computer games and has grown into an event followed worldwide, with 200,000 people voting for this year's winners.
Kicking Palantir off of AWS is among their demands, too
Rafaela Vasquez was watching The Voice at the time of the crash, new evidence shows
PUBG price slashed on Steam after selling more than 50 million copies - as daily player numbers plunge
Use the same password for every website? It might be time to change them all