IBM has joined forces with the University of Edinburgh in a five-year project
to accelerate the design of drugs aimed at tackling HIV.
The collaboration will combine IBM's powerful computing technology, including
the Blue Gene supercomputer, with lab techniques aimed at targeting the HIV
infection process.
Researchers will examine peptides, which play a critical role in stimulating
the body's immune response to viral attack.
By understanding the structure and behaviour of the peptide, the research
team hopes to pave the way for the design of multiple drugs capable of targeting
the infection process.
"Our early results show that we can use computers to simulate which molecules
can stop the HIV virus from infecting humans, allowing drug makers to more
rapidly develop those drugs," said Jason Crain, at the University of Edinburgh's
school of physics.
"This is a new approach to drug design. We are using sophisticated algorithms
coupled with experimental techniques to design improved molecular therapies, and
we can capitalise on enormous computing power to do this efficiently and
rationally."
The University of Edinburgh installed Europe's first IBM Blue Gene
supercomputer in 2004 in a bid to help lab experts and researchers throughout
Britain tackle a range of scientific puzzles.
"By combining experimental research and the world's most powerful
supercomputer we just might get much closer to that goal," said IBM researcher
Glenn Martyna.
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